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T. M. Almeida, M. S. Piedade, P. C. Lopes, L. Sousa, J. Germano, F. Cardoso, H. A. Ferreira, P. P. Freitas
MAGNETORESISTIVE BIOSENSOR MODELLING FOR BIOMOLECULAR RECOGNITION

This paper presents the modelling of a magnetic biosensor included on a hand held microsystem based on a fully integrated magnetoresistive biochip for biomolecular recognition (DNA hybridisation, antibody antigen interaction, etc.). The biochip uses magnetic field arraying of magnetically tagged biomolecules and high sensitivity sensors which can be used to detect single or few biomolecules. The biosensor has an matrix-array structure and each biosensor site consists of a thin film diode in series with a magnetic tunnel junction. Schottky and pin diodes are used as temperature sensors and switching devices, although this paper specially emphasises pin diodes characterisation. A complete theoretical model characterising biosensor electrical, temperature and magnetic behaviour is derived and experimental results are provided.

T. Katsumata, H. Aizawa, Y. Kakinuma, E. Matashige, S. Komuro, T. Morikawa
TWO DIMENSIONAL PHOTOLUMINESCENCE IMAGING OF FOOD FOR NON-DESTRUCTIVE QUALITY CONTROL

Non-destructive evaluation technique of the foods including starches has been developed based on photoluminescence from starches in the foods. The visible PL with broad peak at wavelength of λ = 462 nm are observed from various foods including starches, such as polished rice, flour and corn starch, under illumination of ultra-violet (UV) light at λ = 365 nm. Peak intensity is found to vary with the source and the breed of the specimens. PL images from starches also reveal the uniformity of the food products. Two-dimensional images of PL, which revealed the uniformity of foods under UV irradiation, are potentially useful for the evaluation and the quality control of the foods and starchy products.

Vaclav Papez, Stanislava Papezova
INFLUENCE OF A MAGNETIC FIELD ON LIVING TISSUE

This paper describes a system, which enables quantitative monitoring and evaluation of the influence of a pulse magnetic field on a live organism by using of bioimpedance measurement. There are presented results of performed experiments.

Rodrigo P. B. da Costa-Felix, André Victor Alvarenga, Marissa A. Rivera Cardona
THE BRAZILIAN NATIONAL LABORATORY OF ULTRASOUND

Aiming to support the national metrology on ultrasound, Inmetro, the Brazilian National Institute of Metrology (NMI), has been putting effort on its Laboratory of Ultrasound (Labus). In a first approach, Labus is able to offer traceability in basically four general areas: Ultrasonic (US) Transducer Calibration, US Power Measurement, US Field Mapping, and Reference Materials Certification for US applications. The frequency range Labus firstly established its calibration and testing methods is from 0.5 MHz to 20 MHz, being the limits dependent on the particular application considered. So far, Labus most important facilities consist in two water tanks, three manuals and one complete remote-controlled micro-positioning systems, three equipments sets to generate and acquire US signals (arbitrary waveform generators and scopes-like instruments), a set of transducers and primary standards in Power Measurement (a stable US power source) and Hydrophone Calibration (two membrane hydrophones). For while, Labus is traced to others NMI, but the goal is to implement absolute calibration methods in two years time. Within this paper, Labus will be presented in details, particularly outlining its state of art in Transducer Calibration, Power Measurement, and Reference Materials Certification. Join ventures with industry and private and universities laboratories will be outlined, either.

Marissa A. Rivera Cardona, André Victor Alvarenga, Rodrigo P. B. da Costa-Felix
PRIMARY LEVEL ULTRASONIC OUTPUT POWER MEASUREMENT AT LABORATORY OF ULTRASOUND OF INMETRO

The primary level ultrasonic output power measurement service is being set up at the Laboratory of Ultrasound (Labus) of Inmetro, based on the standard IEC 61161. Labus´ main purpose is to provide support, in accordance with procedures developed by its services, to industry, to calibration laboratories, and to final consumers (patients, for instance). Labus’ clients will have means and necessary data to obtain, between other things, pre-market approvals of new models or equipment, laboratory accreditation, and on demand checks of equipment already being in use. These procedures will ensure optimized and safe use of ultrasound technology at all levels. This paper presents the main characteristics of Labus’ primary level ultrasonic output power measurement service.

Luís Pina Soares, Raul Carneiro Martins
NON-LINEAR FIT OF A 6 SKEWED GAUSSIAN TEMPLATE FOR FILTERING, COMPRESSION AND CLINICAL IDENTIFICATION OF THE ECG USING A DSP WIRELESS SETUP

In this paper we present an improved method for the acquisition, filtering, compression and clinical parameter identification of the ECG. The method involves the use of an improved instrumentation setup with high resolution and sample rate, as well as DSP monitored automatic gain and offset control (AGOC) which maximizes the range of the signal. It also involves the fitting of the signal with a nonlinear model consisting of six generalized Gaussians (with skew). The method further includes the use of sinefitting techniques to selectively remove electromagnetic interference such as the power-line (50 Hz or 60 Hz component). We will further describe the experimental setup developed, which is a DSP based portable 3-lead device, and show some experimental and characterization results.

Jarkko Mäkiranta, Jukka Lekkala
OPTIMIZATION OF A NOVEL MAGNETIC NANOPARTICLE SENSOR

This paper represents an experimental iteration of a novel magnetic nanoparticle (MNP) sensor. MNPs can be used as labels in quantitative diagnostic. Planar microcoils in an impedance bridge are used to measure the amount of the particles. Particles change the inductance of the coil due to their permeability. The shape and size of the coil are critical to the sensitivity and robustness. Experimental measurements supported by numerical simulations have been used in sensor designing, improving and optimization.

J.T. Filho, L.R. Lidízio, L.A. Sena, J.C. Damasceno, C.A. Achete
TITANIUM OXIDE FILMS PRODUCED BY MICRO-ARC OXIDATION FOR HIGH PERFORMANCE TITANIUM IMPLANTS

The growth of titanium oxide layer on titanium surface by the micro-arc oxidation technique was investigated. Ca(CH3COO)2 (0.3M), Na2CO3 (0.6M) and Na2HPO4 (0.1M) solutions were employed as electrolytes. SEM and EDS microanalysis were used for morphology, composition characterization and low-angle X-ray diffraction to describe titanium oxide crystallographic orientation. TiO2 films formed by using 0.3M Ca(CH3COO)2 and 0.1M Na2HPO4 solutions showed a porous, homogeneous surface structure, with presence of phosphorous and after an hydrothermical treatment using a Ca(OH)2 suspension during 24h at 60ºC was observed phosphorous and calcium.

Gregor Geršak, Valentin Batagelj, Janko Drnovšek
OSCILLOMETRIC VIRTUAL INSTRUMENT FOR BLOOD PRESSURE MEASUREMENT

In this paper a simple educational model of a non-invasive blood pressure measurement device, based on the oscillometric principle is presented. The device is composed of a pressure transducer, auxiliary instrumentation for signal acquirement and digital signal processing module in the LabVIEW environment. Since the most problematic part of metrological evaluation of oscillometric devices is in proprietary algorithms of determining systolic and diastolic blood pressure, two basic algorithms are discussed. The amplitude algorithm is used for building the virtual instrument (VI). Preliminary comparisons of the built VI were done using simulated and real person's blood pressure waveform. The VI proved to be a useful tool for studying amplitude algorithms of determining systolic and diastolic pressure from the oscillations envelope.

Elton Gomes Pereira
PROPOSAL OF A NEW METHOD FOR ASSESSING THE AMBIENT DOSE EQUIVALENT, WHICH ACCOUNTS FOR THE INFLUENCE OF THE HIGH VOLTAGE IN A MEDICAL X RAY FACILITY

Two methods of radiological survey in a medical X ray room are compared. The first method is just the usual one, as done today in Brazil. It is based on the election of a high voltage (HV) value, by legal rule the highest used in the clinic, taken as a standard. This highest HV value is supposed to be constant and representative of all others values, which are simply ignored. This work shows that the results of this approach move away a bit from the actual radiation doses, overestimating the values. A second method is proposed and compared with the first one. It takes the various values of HV into account. One should only assume a quadratic relationship between the dose measurements and HV and change the way of workload data acquirement. This second method presents a modified way to calculate the ambient equivalent dose [H*(10)]. It is shown that the spread of values present by the 2nd method is smaller than that of the current one, although in the 2nd method the values are still overestimated, however not too much. Putting both methods side by side, as a conclusion, the second one shows to be better than the first, as it adheres more to the reality.

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