Different behavior of food polyphenols from Theobroma cacao in energy metabolism of lipopolysaccharide-stimulated cells

de la Luz Cádiz-Gurrea, M., Fernández-Arroyo, S., Joven, J., Segura-Carretero, A.
Abstract:
Theobroma cacao is worldwide consumed and common ingredient of many food products. Cocoa, containing high-degree of polymerization proanthocyanidins, is a valuable source of bioactive compounds. Mouse embryonic fibroblast (MEF) cell lines, PON-1 KO and MCP-1 KI, were used as potential oxidant and inflammatory scenarios, respectively. Energy metabolism changes drastically when MEF are incubated with LPS. Cacao has an important effect on PON-1 KO incubated with LPS, leading metabolite values to these found in WT (particularly those related to the glycolysis).
Keywords:
Theobroma cacao, proanthocyanidins, antiinflamatory, antioxidant, energy metabolism
Download:
IMEKO-TC23-2017-129.pdf
DOI:
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Event details
IMEKO TC:
TC23
Event name:
3rd IMEKOFOODS Conference
Title:

Metrology Promoting Standardization and Harmonization in Food and Nutrition

Place:
Thessaloniki, GREECE
Time:
01 October 2017 - 04 October 2017