Exploring the link between the circulatory and excreted metabolome during pregnancy – A pilot study

Dimitropoulou, A., Fotakis, C., Fotiou, M., Tsakoumaki, F., Kyrkou, C., Menexes, G., Athanasiadis A. P., Biliaderis, C. G., Zoumpoulakis, P., Michaelidou, A. M.
Abstract:
This exploratory research effort describes a metabolomic approach to elucidate the link between the circulatory and excreted metabolome during the 2nd trimester of pregnancy. NMR metabolomics was employed, in order to assess the maternal serum and urine fingerprint. The metabolites were integrated into a metabolic correlation network, to visualize the resulting correlation matrices in circulatory and excreted metabolomes. It would be of outmost importance to capitalize on metabolomics, in order to unravel the biochemical pathways towards further understanding of pregnancy metabolism.
Keywords:
pregnancy, NMR metabolomics, serum, urine, metabolite correlations
Download:
IMEKO-TC23-2017-093.pdf
DOI:
-
Event details
IMEKO TC:
TC23
Event name:
3rd IMEKOFOODS Conference
Title:

Metrology Promoting Standardization and Harmonization in Food and Nutrition

Place:
Thessaloniki, GREECE
Time:
01 October 2017 - 04 October 2017