The role of in vitro simulated human digestion models in assessing potential exposure to nanoparticles in food: an essential tool for risk assessment of nanomaterials used in food-related applications |
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| Cubadda, F., Aureli, F., Raggi, A., Mantovani, A. |
- Abstract:
- In the food sector, applications of nanotechnologies to (i) agricultural production, (ii) food processing, and (iii) food contact materials are rapidly developing. An appropriate nano-specific risk assessment has to be carried out for nanotechnology applications that result in the presence of nanoparticles in food. One essential issue in such an assessment is to ascertain whether there is potential for systemic exposure, i.e., if nanoparticles may persist as such after gastrointestinal digestion and be absorbed in the gut. The importance of studying the dissolution of nanoparticles under conditions representative of the gastrointestinal tract is discussed, along with the in vitro models and the analytical methods that can be used for such an undertaking.
- Keywords:
- nanotechnology, nanomaterials, risk assessment, human dietary exposure, human digestion models
- Download:
- IMEKO-TC23-2017-017.pdf
- DOI:
- -
- Event details
- IMEKO TC:
- TC23
- Event name:
- 3rd IMEKOFOODS Conference
- Title:
Metrology Promoting Standardization and Harmonization in Food and Nutrition
- Place:
- Thessaloniki, GREECE
- Time:
- 01 October 2017 - 04 October 2017